New Halimane Diterpenoids from Croton oblongifolius

Abstract

Three new halimane-type diterpenoids, crotohalimaneic acid (1), crotohalimoneic acid (2) and 12-benzoyloxycrotohalimaneic acid (3), were isolated from the stem bark of Croton oblongifolius Roxb. Their structures were established on the basis of spectroscopic and X-ray analysis. Compounds 1 and 2 showed non-specific strong cytotoxicity against a panel of human tumor cell lines; whereas 3 was inactive.

References

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