Vilsmeier-Haack Reagents. Novel Electrophiles for the One-Step Formylation of O-Silylated Ethers to O-Formates

Jean-Paul Lellouche; Vadim Kotlyar

doi:10.1055/s-2004-815435

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Vilsmeier-Haack Reagents. Novel Electrophiles for the One-Step Formylation of O-Silylated Ethers to O-Formates

Jean-Paul Lellouche*, Vadim Kotlyar
Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900 Israel
Fax: +972(3)5351250; e-Mail: lellouj@mail.biu.ac.il;

Abstract

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Abstract

Various O-silylated substrates were effectively converted in one-step to their corresponding O-formates using electrophilic racemic and homochiral Vilsmeier-Haack reagents. Reactivity trends of these transformations were examined that, specifically, emphasized their synthetic potential.

Key words

Vilsmeier-Haack complexes - deprotection of O-silyl ethers - one-step deprotection - preparation of O-formates - formyl glycosides

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References

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