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Antipsychotic treatment in schizophrenic patients. 6-month data of the 3-year European observational study of health outcomes (SOHO)
The SOHO study investigates the use and cost-effectiveness of antipsychotic (AP) medication. As part of the current 6-month analysis, patient retention rates and dosages given during the observation period were evaluated and mono- vs. combination therapy was compared.
10,204 patients participate, retention rate after 6 months was 89%, varying from 67% (Netherlands) to 96% (Italy). Retention rates by cohort were highest for depot typicals (93%), followed by clozapine (92%), and lowest for amisulpride (86%). The retention rate for olanzapine was 88%.
The majority of patients (83%) received their AP medication as monotherapy (57% in Portugal to 93% in the Netherlands). Most patients remained on their initial therapy; 73% in Portugal for risperidone and 100% in Spain for clozapine.
At the meeting, data for the 12 month period will also be available.