Pharmacopsychiatry 2003; 36 - 277
DOI: 10.1055/s-2003-825520

Subjective response to psychotropic drugs in psychiatric in-patients

H Spießl 1, M Dobmeier 1, CP Ostermeier 2, HE Klein 1
  • 1Department of Psychiatry and Psychotherapy, University of Regensburg, Germany
  • 2Psychiatric Hospital Castle Werneck, Germany

Objective: The study aimed at evaluating subjective response to psychotropic drugs in psychiatric in-patients. Methods: 570 patients in two psychiatric state hospitals were surveyed using the Drug Attitude Inventory (DAI-10). The response rate was 78% (n=446). Results: 63% of patients attribute more positive characteristics to psychotropic drugs in general. 30% of patients feel like in a daze and 46% feel tired and sluggish. 35% of patients do not take medication of their own choice and 70% of patients report that they take medication only when they are sick. Significant positive predictors for the patients’ experiences are treatment with antidepressants and neuroleptics as well as the diagnosis of an organic psychiatric disorder, whereas the use of hypnotics is a negative predictor. No significant influence could be ascertained regarding age, gender, other main diagnoses, and other psychotropic drugs. Conclusions: As subjective response is predictive for treatment outcome, compliance, and quality of life, the patients’ experiences on psychotropic drugs should be taken into consideration more when deciding on treatment regimen.