Semin Musculoskelet Radiol 2003; 7(3): 217-226
DOI: 10.1055/s-2003-43232
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Imaging of Neuropathic Arthropathy

Piran Aliabadi1 , Nayer Nikpoor2 , Leyla Alparslan1
  • 1Harvard Medical School, Radiologist, Brigham and Women's Hospital, Boston, MA
  • 2Tufts University School of Medicine, Department of Radiology, New England Medical Center, Boston, MA
Further Information

Publication History

Publication Date:
31 October 2003 (online)

ABSTRACT

Neuropathic arthropathy is a chronic, progressive joint degeneration with bone fragmentation, ligamentous instability, and dislocation. Diabetes is the leading cause of neuropathic arthropathy. Conventional radiography is the most commonly used imaging modality for diagnosing neuropathic arthropathy. The disease is mostly the hypertrophic type and is manifested by sclerosis of the bone, fragmentation, joint destruction, swelling, large joint effusion, and large osteophyte formation. Computed tomography, magnetic resonance imaging and radionucleide scintigraphy are helpful for diagnosing the disease and may help in distinguishing neuropathic arthropathy from septic arthritis and osteomyelitis.

REFERENCES

  • 1 Kapila A, Lines M. Neuropathic spinal arthropathy: CT and MR findings.  J Comput Assist Tomog . 1987;  11 736-739
  • 2 Bayne O, Lu E J. Diabetic Charcot's arthropathy of the wrist. Case report and literature review.  Clin Orthop Relat Res . 1998;  357 122-126
  • 3 Palestro C J, Mehta H H, Patel M. Marrow versus infection in the Charcot joint: indium-111 leukocyte and techneticm-99m sulfur colloid scintigraphy.  J Nucl Med . 1998;  39 346-350
  • 4 Brower A C, Allman R M. Pathogenesis of the necrotrophic joint: neurotraumatic vs neurovascular.  Radiology . 1981;  139 349-354
  • 5 Allman R M, Brower A C, Kotlyarov E B. Neuropathic bone and joint disease.  Radio Clin North Am . 1988;  26 1373-1381
  • 6 Jones E A, Manaster B J, May D A, Disler D G. Neuropathic osteoarthropathy: diagnostic dilemmas and differential diagnosis.  Radiographics . 2000;  20 5279-5293
  • 7 Beltran J, Campanin D S, Knight C, McCalla M. The diabetic foot: magnetic resonance imaging evaluation.  Skeletal Radiol . 1990;  19 37-41
  • 8 Edmonds M E. The diabetic foot: pathophysiology and treatment.  Clin Endocrinol Metab . 1986;  15 889-916
  • 9 Deirmengian C A, Lee S GP, Jupiter J B. Neuropathic arthropathy of the elbow. A report of five cases.  J Bone Joint Surg Am . 2001;  83 839-844
  • 10 Park Y H, Taylor J AM, Szollar S M, Resnick D. Imaging findings in spinal neuroarthropathy.  Spine . 1994;  19 1499-1504
  • 11 Wirth C R. Charcot spine.  Spine . 1980;  5 558-567
  • 12 Wagner S C, Schwitzer M E, Morrison W B, Przybylski G J, Parker L. Can imaging findings help differentiate spinal neuropathic arthropathy from disk space infection?.  <~>Initial experience. Radiology . 2000;  214 693-699
  • 13 Gold R H, Tong D JF, Crim J R, Seeger L L. Imaging the diabetic foot.  Skeletal Radiol . 1995;  24 563-571
  • 14 Schauwecker D S, Park H M, Burt R W, Mock B H, Wellman H N. Combined bone scintigraphy and In-111 leukocyte scan in neuropathic foot disease.  J Nucl Med . 1988;  10 1651-1655
  • 15 Gerand S, Dolan M, Laing P ML, Kleverman L. Diagnosis of osteomyelitis in neuropathic ulcers.  J Bone Joint Surg Br . 1996;  78 5-15
  • 16 Meller J, Koster G, Liersch T. Chronic bacterial osteomyelitis: prospective comparison of F-18 FDG imaging with dual head coincidence camera and In-111 labeled autologous leuckocyte scintigraphy.  Eur J Nucl Med Mol Imag . 2002;  29 53-60
  • 17 Alnafisi N, Yun M, Alavi A. F-18 FDG position emission tomography to differentiate diabetic osteoarthropathy from septic arthritis.  Clin Nucl Med . 2001;  26 638-639