Planta Med 2003; 69(8): 779-781
DOI: 10.1055/s-2003-42792
Letter
© Georg Thieme Verlag Stuttgart · New York

Halophilols A and B, Two New Stilbenes from Iris halophila

Yong-Qiang Wang1 , Jun-Jie Tan1 , Chang-Heng Tan1 , Shan-Hao Jiang1 , Da-Yuan Zhu1
  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, P.R. China
Further Information

Publication History

Received: November 29, 2002

Accepted: April 26, 2003

Publication Date:
06 October 2003 (online)

Abstract

A new monomeric stilbene, halophilol A (1), and a new tetrastilbene, halophilol B (2), along with three known oligostilbenes were isolated from the seeds of Iris halophila. Their structures were established on the basis of the spectral data. The oligostilbene skeleton is encountered for the first time in the Iridaceae family. Bioactivity tests showed that 1 had moderate cytotoxicity against KB and HMEC cell lines (IC50 = 17.28 μM, 22.47 μM respectively), while 2 was inactive.[*]

Prof. Da-Yuan Zhu

Shanghai Institute of Materia Medica

Chinese Academy of Sciences

294 Taiyuan Road

Shanghai 200031

P. R. China

Fax: +86-21-64370269

Email: dyzhu@mail.shcnc.ac.cn