Planta Med 2003; 69(5): 434-439
DOI: 10.1055/s-2003-39716
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Diterpenoid and Phenolic Glycosides from the Roots of Rhododendron molle

Guan-Hu Bao1 , Li-Quan Wang1 , Kin-Fai Cheng2 , Yong-Hong Feng1 , Xiao-Yu Li1 , Guo-Wei Qin1
  • 1Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, P. R. China
  • 2Department of Chemistry, The University of Hong Kong, Hong Kong, P. R. China
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Publikationsverlauf

Received: September 24, 2002

Accepted: February 9, 2003

Publikationsdatum:
12. Juni 2003 (online)

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Abstract

Two new grayanane diterpenoid glucosides, rhodomosides A (1), B (2) and two new phenolic glycosides 3, 4 together with a known glucosyringic acid (5) were isolated from the roots of Rhododendron molle G. Don (Ericaceae). Their structures were elucidated on the basis of spectral analysis. Compounds 3, 4 and 5 were found to inhibit the proliferation of murine B lymphocytes in vitro, while compound 3 also showed stimulatory activity on the proliferation of murine T lymphocytes in vitro.

References

Prof. Guo-wei Qin

Shanghai Institute of Materia Medica

Shanghai Institutes for Biological Sciences

Chinese Academy of Sciences

294 Tai-Yuan Road

Shanghai 200031

People’s Republic of China

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