First Isolation of a Symmetrical Glycosylated Methylene Bisflavonoid

Abstract

Blutaparon portulacoides (St. Hil.) Mears (= Philoxerus portulacoides St. Hil.) (Amaranthaceae) is a species occurring in the Brazilian coast in two botanical varieties. The chemical study of an ethanolic extract led to the isolation of spinacetin 3-O-robinobioside as well as an unique glycosylated pseudo-dimeric flavonoid identified as 8,8″″-methylene bis(spinacetin 3-O-robinobioside) mainly by NMR analyses (¹H, ¹H-¹H COSY, ¹³C, HMQC, HMBC) and MALDI-TOF mass spectrometry.

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