Planta Med 2003; 69(4): 367-369
DOI: 10.1055/s-2003-38880
© Georg Thieme Verlag Stuttgart · New York

Anti-Inflammatory and Analgesic Effects of a Mixture of Fatty Acids Isolated and Purified from Sugar Cane Wax Oil

N. Ledón1 , A. Casacó1 , V. Rodríguez1 , J. Cruz1 , R. González1 , Z. Tolón1 , M. Cano1 , E. Rojas1
  • 1National Center for Scientific Research, Havana, Cuba
Further Information

Publication History

Received: August 28, 2002

Accepted: December 2, 2002

Publication Date:
23 April 2003 (online)


The anti-inflammatory and analgesic effects of FAM, a defined mixture of fatty acids isolated from sugar cane (Saccharum officinarum L.), was evaluated. Oral administration of this mixture showed anti-inflammatory activity in the cotton pellet granuloma assay and in the carrageenin-induced pleurisy test, both in rats, as well as in the peritoneal capillary permeability test in mice. In addition, FAM showed analgesic properties in the hot-plate model and in the acetic acid-induced writhings test, both in mice. In conclusion, these results provide evidence on the potential usefulness of the mixture of fatty acids from sugar cane wax oil in inflammatory disorders.


Dra. Naris Ledon

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