Abstract
Some ester derivatives of salonitenolide have been prepared from cnicin, a germacranolide
sesquiterpenoid. The compounds were tested for their antibacterial activity. The 8,15-diesters
showed a good activity, comparable with that of cnicin. The 15-monoester compounds
were not very active showing that esterification at the C-8 position is an important
structural feature for antibacterial properties.
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Prof. Maurizio Bruno
Dipartimento di Chimica Organica ”E. Paternò”
Università di Palermo
Viale delle Scienze
Parco d’Orleans II
90128 Palermo
Italy
Phone: +39-0915-96905
Fax: +39-0915-96825
Email: bruno@dicpm.unipa.it
