Isolation and X-Ray Study of an Anti-Inflammatory Active Androstene Steroid from Acacia nilotica

Abstract

3β-Acetoxy-17β-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse earedema.

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