Pneumologie 2003; 57(3): 144-148
DOI: 10.1055/s-2003-37739
Der interessante Fall
© Georg Thieme Verlag Stuttgart · New York

Das Yellow-Nail-Syndrom

The Yellow Nail SyndromeM.  Riedel1 , V.  Bohanes2
  • 1Deutsches Herzzentrum, Technische Universität München
  • 2Bezirks-Krankenhaus, St. Johann in Tirol, Österreich
Further Information

Publication History

Eingang: 20. November 2002

Nach Überarbeitung angenommen: 30. Januar 2003

Publication Date:
10 March 2003 (online)

Zusammenfassung

Es wird der Fall einer 54-jährigen Frau mit Yellow-nail-Syndrom mit Pleuraergüssen, Lymphödem, Perikarderguss, Rhinosinusitis und Bronchiektasien beschrieben. Das Fallbeispiel illustriert einen eher benignen Verlauf des Syndroms über 10 Jahre. Das Yellow-nail-Syndrom sollte in differenzialdiagnostische Überlegungen bei bilateralen Pleuraergüssen mit einbezogen werden.

Abstract

A case of a 54-year-old woman exhibiting the yellow nail syndrome with exudative pleural effusions, lymphoedema, pericardial effusion, rhinosinusitis and bronchiectasis is described. This case illustrates the rather benign course of the syndrome over ten years. A review of the literature is provided. The etiology of the syndrome is obscure, while the pathogenesis seems to involve impaired lymphatic drainage. The entity should be considered in the differential diagnosis of bilateral pleural effusion. It is likely that the condition is not as rare as it appears from the number of published reports, and a greater awareness of its various forms will probably lead to more frequent diagnosis.

Literatur

  • 1 Samman P D, White W F. The „yellow nail” syndrome.  Br J Dermatol. 1964;  76 153-157
  • 2 Emerson P A. Yellow nails, lymphedema and pleural effusions.  Thorax. 1966;  21 249-253
  • 3 Hiller E, Rosenow E CD, Olsen A M. Pulmonary manifestations of the yellow nail syndrome.  Chest. 1972;  61 452-458
  • 4 Nordkild P, Kromann-Andersen H, Struve-Christensen E. Yellow nail syndrome - the triad of yellow nails, lymphedema and pleural effusions. A review of the literature and a case report.  Acta Med Scand. 1986;  219 221-227
  • 5 Varney V A, Cumberworth V, Sudderick R. et al . Rhinitis, sinusitis and the yellow nail syndrome: a review of symptoms and response to treatment in 17 patients.  Clin Otolaryngol. 1994;  19 237-240
  • 6 Iqbal M, Rossoff L J, Marzouk K A. et al . Yellow nail syndrome: resolution of yellow nails after successful treatment of breast cancer.  Chest. 2000;  117 1516-1518
  • 7 Malek N P, Ocran K, Tietge U J. et al . A case of the yellow nail syndrome associated with massive chylous ascites, pleural and pericardial effusions.  Z Gastroenterol. 1996;  34 763-766
  • 8 Radenbach K L, Wundschock M. Yellow-nail-Syndrome mit Pleuritis exsudativa, Krankheit der Atemwege, Skleronychie und Lymphangiopathie sowie Nephropathie als Besonderheit.  Prax Pneumol. 1974;  28 1139-1145
  • 9 D'Alessandro A, Muzi G, Monaco A. et al . Yellow nail syndrome: does protein leakage play a role?.  Eur Respir J. 2001;  17 149-152
  • 10 Runyon B A, Forker E L, Sopko J A. Pleural-fluid kinetics in a patient with primary lymphedema, pleural effusions, and yellow nails.  Am Rev Respir Dis. 1979;  119 821-825
  • 11 Solal-Celigny P, Cormier Y, Fournier M. The yellow nail syndrome. Light and electron microscopic aspects of the pleura.  Arch Pathol Lab Med. 1983;  107 183-185
  • 12 Wiggins J, Strickland B, Chung K F. Detection of bronchiectasis by high-resolution computed tomography in the yellow nail syndrome.  Clin Radiol. 1991;  43 377-379
  • 13 Miro A M, Vasudevan V, Shah H. Ciliary motility in two patients with yellow nail syndrome and recurrent sinopulmonary infections.  Am Rev Respir Dis. 1990;  142 890-891
  • 14 Morandi U, Golinelli M, Brandi L. et al . „Yellow nail syndrome” associated with chronic recurrent pericardial and pleural effusions.  Eur J Cardiothorac Surg. 1995;  9 42-44
  • 15 Wakasa M, Imaizumi T, Suyama A. et al . Yellow nail syndrome associated with chronic pericardial effusion.  Chest. 1987;  92 366-367
  • 16 DeCoste S D, Imber M J, Baden H P. Yellow nail syndrome.  J Am Acad Dermatol. 1990;  22 608-611
  • 17 Jiva T M, Poe R H, Kallay M C. Pleural effusion in yellow nail syndrome: chemical pleurodesis and its outcome.  Respiration. 1994;  61 300-302
  • 18 Glazer M, Berkman N, Lafair J S. et al . Successful talc slurry pleurodesis in patients with nonmalignant pleural effusion.  Chest. 2000;  117 1404-1409

Doz. Dr. Med. M. Riedel, FESC

Deutsches Herzzentrum und I. Medizinische Klinik, Technische Universität München

Lazarettstraße 36

80636 München

Email: m.riedel@dhm.mhn.de

    >