Planta Med 2003; 69(2): 158-161
DOI: 10.1055/s-2003-37714
© Georg Thieme Verlag Stuttgart · New York

Composition and Antimicrobial Activity of the Essential Oil of Artemisia absinthium from Croatia and France

Fabien Juteau1 , Igor Jerkovic3 , Véronique Masotti1 , Mladen Milos3 , Josip Mastelic3 , Jean-Marie Bessière2 , Josette Viano1
  • 1Laboratoire Dynamique et Ressources du Végétal, E.A. 2202 - Biodiversité, Université de Provence, Marseille, France
  • 2Ecole Nationale Supérieure de Chimie de Montpellier, CNRS URA 1193, Montpellier, France
  • 3Faculty of Chemical Technology, Department of Organic Chemistry, Split, Croatia
Further Information

Publication History

Received: May 16, 2002

Accepted: October 20, 2002

Publication Date:
07 March 2003 (online)


The essential oils obtained by steam distillation from the aerial parts of two populations of Artemisia absinthium, from France and from Croatia, were analyzed by GC and GC-MS. The oils of A. absinthium of French origin contain (Z)-epoxyocimene and chrysanthenyl acetate as major components while the oils of Croatian A. absinthium contain mainly (Z)-epoxyocimene and β-thujone. Analysis of oils before and after anthesis showed some quantitative differences. Analysis of separated leaves and flowering heads showed only few differences among these organs. As they contain no thujone, antimicrobial screening was performed on samples of French origin and showed that A. absinthium oil inhibited the growth of both tested yeasts (Candida albicans and Saccharomyces cerevisiae var. chevalieri).


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