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DOI: 10.1055/s-2002-38131
© Georg Thieme Verlag Stuttgart · New York
Epidermoidzyste und endometrioides Karzinom des Ovars: Wo liegt ihr Ursprung?
Ovarian Epidermoid Cyst and Endometrioid Carcinoma: Do they Share their Origin?Publication History
Publication Date:
24 March 2003 (online)
Zusammenfassung
Wir beschreiben das Auftreten eines gut differenzierten endometrioiden Adenokarzinoms und einer Epidermoidzyste in unmittelbarer Nachbarschaft zueinander in einem Ovar. Die Zyste besaß, wie für eine Epidermoidzyste typisch, keine Hautanhangsgebilde. Direkt benachbart lag ein endometrioides Adenokarzinom mit einigen Herden plattenepithelialer Metaplasie. Es bestand keine Kontinuität zwischen den Foci mit plattenepithelialer Metaplasie und der Epidermoidzyste. Zusätzlich besaßen die benigne Zyste und das Karzinom gemeinsame immunhistochemische Merkmale. Diese Kasuistik beleuchtet die immer noch unbeantwortete Frage nach dem Ursprung der Epidermoidzysten und unterstützt die Hypothese, dass sie von pluripotentem Zölomepithel abstammen.
Abstract
A case of a well differentiated endometrioid adenocarcinoma of the ovary in combination with an epidermoid cyst is described. A typical epidermoid cyst without skin appendages could be observed. In direct neighborhood, there was a typical endometrioid carcinoma with some foci of squamous metaplasia. There was no continuum between the squamous metaplasia of the carcinoma and the wall of the epidermoid cyst. In addition, the benign cyst and the carcinoma shared some of their immunohistochemical profile. This case highlights the still unsolved question about the origin of epidermoid cysts and adds to the hypothesis that they arise from pluripotent coelomic epithelium.
Schlüsselwörter
Epidermoidzyste - endometrioides Karzinom - Ovar - Ursprung
Key words
Epidermoid cyst - endometrioid carcinoma - ovary - origin
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Dr. Katharina Peters
Institut für Allgemeine Pathologie der Universität Kiel
Michaelisstr. 11
24105 Kiel
Phone: +49/4 31-5 97 34 85
Fax: +49/4 31-5 97 34 28