Abstract
Essential oil obtained by micro-distillation and hydrodistillation of the endemic
Ferulago thirkeana (Boiss.) Boiss. (Apiaceae) was analysed by GC/MS. An unknown component isolated from
the essential oil was characterized by chromato-spectral techniques (1D-, 2D-NMR,
HRMS, IR and UV) as (1S)-2,6,6-trimethyl-4-oxobicyclo[3.1.1]hept-2-enyl(2E)-2-methylbut-2-enoate (= ferulagone or 1-angeloyloxyverbenone) (1). Biological activities of the essential oil and the purified major component (1) were tested against various human pathogenic microorganisms resulting in moderate
inhibition (62.5 - 125 μg/ml).
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Prof. Dr. K. Hüsnü Can Başer
Medicinal and Aromatic Plant and Drug Research Centre (TBAM)
Anadolu University
26470-Eskişehir
Turkey
Email: khcbaser@anadolu.edu.tr or khcbaser@yahoo.co.uk
Fax: +90 222 335 01 27
