High Frequency Stimulation of the Basal Ganglia for the Treatment of Movement Disorders: Current Status and Clinical Results

V. M. Tronnier; W. Fogel; M. Krause; M. M. Bonsanto; J. Tronnier; A. Heck; K. Münkel; S. Kunze

doi:10.1055/s-2002-32495

min - Minimally Invasive Neurosurgery, Inhaltsverzeichnis

Minim Invasive Neurosurg 2002; 45(2): 91-96
DOI: 10.1055/s-2002-32495

Original Article

High Frequency Stimulation of the Basal Ganglia for the Treatment of Movement Disorders: Current Status and Clinical Results

V. M. Tronnier¹ , W. Fogel² , M. Krause² , M. M. Bonsanto¹ , J. Tronnier¹ , A. Heck¹ , K. Münkel¹ , S. Kunze¹

¹Department of Neurological Surgery, University Hospital, Heidelberg College of Medicine, Germany
²Department of Neurology, University Hospital, Heidelberg College of Medicine, Germany

Abstract

High frequency stimulation of the basal ganglia has gained much interest during the last years. Based on the reevaluation of the results of functional neurosurgery for movement disorders from Leksell's group, pallidotomy as lesional procedure was the first functional operation that underwent a renaissance for the treatment of movement disorders. The work by Benabid and Siegfried who carried out thalamic high frequency stimulation to suppress tremor, the knowledge about deep brain stimulation (DBS) for the treatment of chronic pain as well as better understanding in basal ganglia physiology and the development of reliable stimulation hardware led to an increasing number of centers worldwide who currently apply high frequency DBS for different movement disorders. In the present review the current status of DBS for movement disorders is presented and the results with high frequency stimulation targeted at different brain areas are summarized.

Key words

Basal Ganglia - Deep Brain Stimulation - Dystonia - Essential Tremor - Globus Pallidus - Parkinson's Disease - Subthalamic Nucleus - Thalamus

Volltext

Referenzen

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Prof. Dr. V. M. Tronnier, M.D.

Department of Neurological Surgery · University Hospital · Heidelberg College of Medicine

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