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Planta Med 2002; 68(4): 377-379
DOI: 10.1055/s-2002-26748
DOI: 10.1055/s-2002-26748
Letter
© Georg Thieme Verlag Stuttgart · New York
Constituents of Burasaïa madagascarensis: A New Clerodane-Type Diterpene
Weitere Informationen
Publikationsverlauf
June 22, 2001
September 30, 2001
Publikationsdatum:
02. Mai 2002 (online)

Abstract
From an ethanol extract of the stems of Burasaïa madagascarensis Thouars (Menispermaceae) were isolated N-acetylnornuciferine and two clerodane-type diterpenes, one of them, epicordatine, being new. The structures were established by the interpretation of the spectral data. All the described compounds exhibited weak antimalarial activity.
References
- 1 Rasoanaivo P, Ratsimamanga-Urverg S, Rakoto-Ratsimamanga A, Raharisololalao A. Constituants chimiques de trois espèces de Burasaïa (Ménispermacées) endémiques de Madagascar. Biochemical Systematics and Ecology. 1991; 19 433-7
- 2 Resplandy A. Sur les alcaloïdes du Burasaïa madagascariensis. Comptes Rendus Académie des Sciences (Paris), 1958; 247 : 2428 - 31; Thèse de Doctorat ès Sciences. Université de Paris Paris; 1958
- 3 Hufford C D. Four new N-acetylnoraporphine alkaloids from Liriodendron tulipifera . Phytochemistry. 1976; 15 1169-71
- 4 Martin M T, Frappier F, Rasoanaivo P, Randrianarivelojosia M. Spectral assignment of strychnobrasiline. Magnetic Resonance Chemistry. 1996; 34 489-91
- 5 Achenbach H, Hemrich H. Clerodane-type diterpenes and other constituents of Penianthus zenkeri . Phytochemistry. 1991; 30 1957-62
- 6 Dadoun H, Muller A H, Cesario M, Guilhem J, Pascard C. Cordatin, a new diterpene from Apasristhmium cordatum . Phytochemistry. 1987; 26 2108-10
- 7 Overton K H, Weir N G, Wylie A. The stereochemistry of the Colombo root bitter principles. Journal of the Chemical Society 1966: 1482-90
- 8 Tuntiwachwuttikul P, Boonrasri N, Bremner J B, Taylor W C. Rearranged clerodane diterpenes from Tinospora baenzigeri . Phytochemistry. 1999; 52 1335-40
- 9 Wright C W, Phillipson J D. Natural products and the development of selective antiprotozoal drugs. Phytotherapy Research. 1990; 4 127-39
- 10 Frappier F, Jossang A, Soudon J, Calvo F, Rasoanaivo P, Ratsimamanga-Urverg S, Saez J, Schrével J, Grellier P. Bisbenzylisoquinoleines as modulators of chloroquine resistance in Plasmodium falciparum and multidrug resistance in tumor cells. Antimicrobial Agents Chemotherapy. 1996; 40 1476-81
Dr. François Frappier
Laboratoire de Chimie des Substances Naturelles, ESA 8041 CNRS
Muséum National d"Histoire Naturelle
63 rue Buffon, 75231 Paris Cedex 05, France
eMail: frappier@mnhn.fr.
Fax: +33-01-40-79-31-35