Background: The aim of the present study was to assess the anthropometric characteristics and body composition in type 1 diabetic patients and compare the results with a randomly selected control population. Material and Methods: We studied 75 type 1 diabetic patients, 43 male and 32 female, recruited from consecutive diagnosed type 1 diabetic patients attending the Endocrine Unit and treated with a intensive insulin regimen, and 93 control subjects, 44 males and 49 females representative of the census of this city. We performed a dietary recall in patients and determined anthropometric characteristics, both in patients and controls, body weight, height, body-mass index, waist-hip ratio and body composition parameters: total body water, free-fat mass, body free-fat mass, fat mass and body fat by bioelectrical impedance analyser. Results: In diabetic male patients, we observed lower waist-hip ratio than in controls, 0.84 ± 0.06 vs. 0.88 ± 0.07, p = 0.021, higher free-fat mass in female diabetic patients, 48.5 ± 5.6 vs. 45.6 ± 5.9 kg, p = 0.03, lower fat mass in male diabetic patients, 9.5 ± 6.9 vs. 14.6 ± 8.5 kg, p = 0.003. We did not find any correlation among the parameters of body composition and dietary macronutrient intake in patients. Conclusions: The present study exposes the differences in anthropometric characteristics and body composition in type 1 diabetes mellitus, especially lower waist-hip ratio in male, higher free-fat mass in female and lower fat mass in male.
Key words:
Body Composition - Body-Mass Index - Body Surface Area - Free-Fat Mass - Fat Mass - Type 1 Diabetes Mellitus - Waist-Hip Ratio
References
-
1
Heymsfield S B, Matthews D.
Body composition: research and clinical advances - 1993. A.S.P.E.N. research workshop.
J Par Ent Nutr.
1994;
18
91-103
-
2
De Boer H, Block G -J, van der Veen E A.
Clinical aspects of growth hormone deficiency in adults.
Endocr Rev.
1995;
16
63-86
-
3
Cuneo R C, Judd S, Wallace J D, Perry-Keene D, Burger H, Lim-Tio S.
The Australian multicenter trial of growth hormone (GH) treatment in GH-deficient adults.
J Clin Endocrinol Metab.
1998;
83
197-216
-
4
Gómez Sáez J M, Gómez Arnaiz N, Soler Ramón J.
Modificaciones de la composición corporal en pacientes adultos con hipopituitarismo después del tratamiento sustitutivo con hormona de crecimiento.
Med Clin (Bar).
1999;
113
246-249
-
5
Seppel T, Kosel A, Schlaghecke R.
Bioelectrical impedance assessment of body composition in thyroid disease.
Eur J Endocrinol.
1997;
136
493-498
-
6
Tjellesen L, Staun M, Rannem T, Nielsen P K, Jarnum S.
Body composition in patients on home parenteral nutrition.
Scand J Clin Lab Invest.
1996;
56
295-303
-
7
Egger N G, Carlson M S, Shaffer J L.
Nutritional status and assessment of patients on home parenteral nutrition: anthropometry, bioelectrical impedance, or clinical judgment?.
Nutrition.
1999;
15
1-6
-
8
Molina A, Pita A M, Virgili N, Farriols N, Soler J, Gómez J M.
Serum leptin levels in patients with short-bowel syndrome.
Clin Nutr.
2000;
19
333-338
-
9
Anonymus .
NIH Consensus statement. Bioelectrical impedance analysis in body composition measurement. National Institute of Health technology assessment conference statement. December 12 - 14, 1994.
Nutrition.
1996;
12
749-762
-
10
Bartz J, Sulzbach U, Heinze E, Teller W M, Holl R W.
Körperzusammensetzung bei Typ-I-Diabetes mellitus. Bioimpedanzmessungen bei 274 diabetischen Kindern, Jugendlichen und jungen Erwachsenen.
Deutsch Med Wochenschr.
1997;
122
815-819
-
11
Leiter L A.
Use of bioelectrical impedance analysis measurements in patients with diabetes. The Diabetes Control and Complications Trial Research Group.
Am J Clin Nutr.
1996;
64 (3 Suppl)
515-518
-
12 World Health Organization .Diabetes Mellitus: Report of a WHO Study Group. Geneva:; World Health Org (Tech. Rep. Ser., no. 727), 1985
-
13
Fernández-Castañer M, Molina A, López-Jiménez L, Gómez J M, Soler J.
Clinical presentation and early course of type 1 diabetes mellitus in patients with and without thyroid autoimmunity.
Diabetes Care.
1999;
22
377-381
-
14
Backer J, Detsky A, Wesson D, et al.
Nutritional assessment: a comparison of clinical judgement and objective measurements.
N Engl J Med.
1982;
306
967-972
-
15
DuBois D, DuBois E F.
Clinical calorimetry. X. A formula to estimate the approximate surface area in height and weight to be known.
Arch Intern Med.
1916;
17
863
-
16
Lukaski H C, Johnson P E, Bolonchuk W W, Lykken G I.
Assessment of fat-free mass using bioelectrical impedance measurements of the human body.
Am J Clin Nutr.
1985;
41
810-817
-
17 Rossner B. Fundamentals of Biostatistics. 3rd edition. Boston:; PWS-Kent Publishing, 1990
-
18
The DCCT Research Group.
Weight gain associated with intensive therapy in the diabetes control and complication trial.
Diabetes Care.
1988;
11
567-573
-
19
Ferrante E, Pitzalis G, Vania A, et al.
Nutritional status, obesity and metabolic control in children with type 1 diabetes mellitus.
Min Ped.
1999;
51
39-46
-
20
Rigalleau V, Delafaye C, Baillet L, et al.
Composition of insulin-induced body weight gain in diabetic patients: a bio-impedance study.
Diab Metab.
1999;
25
321-328
-
21
Svenson O L, Hassager C.
Body composition and fat distribution measured by dual-energy x-ray absorptiometry in premenopausal and postmenopausal insulin-dependent and non-insulin-dependent diabetes mellitus patients.
Metabolism: Clin & Exp.
1998;
47
212-216
-
22
Sinha A, Formica C, Tsalamandris C, et al.
Effects of insulin on body composition in patients with insulin-dependent and non-insulin-dependent diabetes.
Diab Med.
1996;
13
40-46
-
23
Björntorp P.
Portal adipose tissue as generator or risk factors for cardiovascular disease and diabetes.
Arteriosclerosis.
1990;
10
493-496
-
24
Kiess W, Anil M, Blum W F, et al.
Serum leptin levels in children and adolescents with insulin-dependent diabetes mellitus in relation to metabolic control and body mass index.
Eur J Endocrinol.
1998;
138
501-509
-
25
Gómez J M, Molina A, Fernández-Castañer, Casamitjana R, Martínez-Matos J A, Soler J.
Insulin regulation of leptin synthesis and secretion in humans: the model of myotonic dystrophy.
Clin Endocrinol (Oxf).
1999;
50
569-575
-
26
Gómez J M, Molina A, Fernández-Castañer M, Soler J.
Leptin in type 2 diabetic or myotonic dystrophy women.
Horm Metab Res.
2001;
33
246-249
-
27
Lukaski H C, Bolonchuk W W, Hall C B, Siders W A.
Validaton of tetrapolar bioelectrical impedance method to assess human body composition.
J Appl Physiol.
1986;
69
1327-1332
-
28
Heymsfield S B, Wang Z, Visser M, Gallagher D, Pierson R N Jr.
Techniques used in the measurement of body composition: an overview with emphasis on bioelectrical impedance analysis.
Am J Clin Nutr.
1996;
64 (Suppl 3)
478-484
-
29
Demura S, Kobayashi H, Tanaka K, Sato S, Nagasawa Y, Murase T.
Comprehensive evaluation of selected methods for assessing human body composition.
App Hum Sci.
1999;
18
43-51
-
30
Lukaski H C.
Requirements for clinical use of bioelectrical impedance analysis (BIA).
Ann N York Acad Sci.
1999;
873
72-76
Dr. J. M. Gómez
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