ABSTRACT
The diagnosis of acute pulmonary embolism (PE) remains difficult, and diagnostic strategies
must consider the unique challenges of hospitalized and critically ill patients. Diagnostic
algorithms that are effective and safe for outpatients may not be effective and safe
for inpatients or patients in intensive care units. For example, serial compression
ultrasonography (US) of the lower extremities may allow physicians to avoid pulmonary
angiography for stable inpatients or outpatients, but this strategy is not validated
for patients who require intensive care for serious underlying cardiopulmonary disease.
Helical computed tomography (CT) is particularly suited for the evaluation of suspected
PE for inpatients with serious cardiopulmonary disease. However, the safety of withholding
treatment when a helical CT pulmonary angiogram is negative remains to be demonstrated.
Lung perfusion and ventilation scans combined with an assessment of pretest probability
remain important objective tests for the evaluation of many hospitalized patients.
KEYWORD
Pulmonary embolism - venous thromboembolism - critical care medicine