Semin Speech Lang 2001; 22(4): 261-274
DOI: 10.1055/s-2001-17425
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Retained Neuropsychological Abilities of Individuals with Alzheimer's Disease

Tammy Hopper1 , Kathryn A. Bayles1 2 , Esther Kim2
  • 1National Center for Neurogenic Communication Disorders, The University of Arizona, Tucson, Arizona
  • 2Department of Speech and Hearing Sciences, The University of Arizona, Tucson, Arizona
Further Information

Publication History

Publication Date:
27 September 2001 (online)

ABSTRACT

Individuals with Alzheimer's disease (AD) retain certain cognitive abilities over the course of the disease. In this article, we describe retained cognitive-linguistic abilities and the status of activities of daily living (ADLs) of individuals in the early, middle, and late stages of AD. Knowledge of preserved abilities in AD is necessary for clinicians to structure communication-stimulation programs and to train caregivers in the most effective ways to facilitate communication. Using the Global Deterioration Scale (GDS) for staging severity of AD, an outline of preserved abilities by disease stage is provided. Attention, memory, and communication abilities are discussed, and samples of discourse from patients at different stages are included.

REFERENCES

  • 1 Reisberg B, Ferris S H, Leon M J, Crook T. The global deterioration scale for assessment of primary degenerative dementia.  Am J Psychiatry . 1982;  139 1136-1139
  • 2 Reisberg B, Ferris S H, Franssen E. An ordinal functional assessment tool for Alzheimer's-type dementia.  Hosp Commun Psychiatry . 1985;  36 593-595
  • 3 National Alzheimer's Association Website. www.alz.org
  • 4 Rogers W A. Attention and aging. In: Park D, Schwarz N, eds. Cognitive Aging Philadelphia: Taylor and Francis; 2000: 55-71
  • 5 Erickson R J, Goldfinger S D, LaPointe L L. Auditory vigilance in aphasic individuals: detecting nonlinguistic stimuli with full or divided attention.  Brain Cogn . 1996;  30 244-253
  • 6 Perry R J, Watson P, Hodges J R. The nature and staging of attention dysfunction in early (minimal and mild) Alzheimer's disease: relationship to episodic and semantic memory impairment.  Neuropsychologia . 2000;  38 252-271
  • 7 Folstein M F, Folstein S E, McHugh P R. ``Mini-Mental State'': a practical method for grading the cognitive state of patients for the clinician.  J Psychiatr Res . 1975;  12 189-198
  • 8 Lines C R, Dawson C, Preston G C. Memory and attention in patients with senile dementia of the Alzheimer type and in normal elderly subjects.  J Clin Exp Neuropsychol . 1991;  13 691-702
  • 9 Bayles K A, Tomoeda C K. Functional Linguistic Communication Inventory.  Austin, TX: Pro-Ed; 1994
  • 10 Baddeley A D, Hitch G. Working memory. In: Bower GH, ed. The Psychology of Learning and Motivation San Diego, CA: Academic Press; 1974
  • 11 Baddeley A D. Essentials of Human Memory.  East Sussex, UK: Psychology Press; 1999
  • 12 Baddeley A D, Logie R, Bressi S, Della Sala S, Spinnler H. Dementia and working memory.  Q J Exp Psychol . 1986;  38A 603-618
  • 13 Lafleche G, Albert M S. Executive function deficits in mild Alzheimer's disease.  Neuropsychology . 1995;  9 313-320
  • 14 Storandt M, Botwinick J, Danziger W L, Berg L, Hughes C P. Psychometric differentiation of mild senile dementia of the Alzheimer type.  Arch Neurol . 1984;  41 497-499
  • 15 Bayles K A, Tomoeda C K. The Arizona Battery of Communication Disorders of Dementia.  Austin, TX: Pro-Ed; 1993
  • 16 Nebes R D, Martin D C, Horn L C. Sparing of semantic memory in Alzheimer's disease.  J Abnorm Psychol . 1984;  93 321-330
  • 17 Nebes R D. Contextual facilitation of lexical processing in Alzheimer's disease: Intralexical priming or sentence-level priming?.  J Clin Exp Neuropsychol . 1994;  16 489-497
  • 18 Nebes R D, Boller F, Holland A. Use of semantic context by patients with Alzheimer's disease.  Psychol Aging . 1986;  1 261-269
  • 19 Bondi M W, Troster A I. Parkinson's disease: neurobehavioral consequences of basal ganglia dysfunction. In: Nussbaum PD, ed. Handbook of Neuropsychology and Aging New York: Plenum Press 1997: 216-245
  • 20 Heindel W C, Butters N, Salmon D P. Impaired learning of a motor skill in patients with Huntington's disease.  Behav Neurosci . 1988;  102 141-147
  • 21 Eslinger P J, Damasio A R. Preserved motor learning in Alzheimer's disease: implications for anatomy and behavior.  J Neurosci . 1986;  6 3006-3009
  • 22 Heindel W C, Salmon D P, Shults C W, Walicke P A, Butters N. Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients.  J Neurosci . 1989;  9 582-587
  • 23 Beatty W W, Winn P, Adams R L. Preserved cognitive skills in dementia of the Alzheimer type.  Arch Neurol . 1994;  51 1040-1046
  • 24 Beatty W W. Preserved cognitive skills in dementia: implications for geriatric medicine.  J Okla State Med Assoc . 1999;  92 10-12
  • 25 Kempler D, Curtiss S, Jackson C. Syntactic preservation in Alzheimer's disease.  J Speech Hear Res . 1987;  30 343-350
  • 26 Schwartz M, Marin O, Saffran E. Dissociations of language function in dementia: a case study.  Brain Lang . 1979;  7 277-306
  • 27 Kempler D, Almor A, Tyler L K, Andersen E, MacDonald M C. Sentence comprehension deficits in Alzheimer's disease: a comparison of off-line vs.  on-line sentence processing. Brain Lang . 1998;  64 297-316
  • 28 Kempler D, Almor A, MacDonald M C. Teasing apart the contribution of memory and language impairments in Alzheimer's disease: an online study of sentence comprehension.  Am J Speech Lang Pathol . 1998;  7 61-67
  • 29 Patterson K, Graham N, Hodges J R. Reading in dementia of the Alzheimer type: a preserved ability?.  Neuropsychology . 1994;  8 395-407
  • 30 Bayles K A, Tomoeda C K, Trosset M W. Relation of linguistic communication abilities of Alzheimer's patients to stage of disease.  Brain Lang . 1992;  42 454-472
  • 31 Bayles K A, Tomoeda C K, Caffrey J T, Trosset M W. Confrontation naming and auditory comprehension in Alzheimer's disease.  J Speech Lang Pathol Audiol . 1990;  14 15-20
  • 32 Fromm D, Holland A L. Functional communication in Alzheimer's disease.  J Speech Hear Disord . 1989;  54 535-540
  • 33 Orange J B, Purves B. Conversational discourse and cognitive impairment: implications for Alzheimer's disease.  J Speech Lang Pathol Audiol . 1996;  20 139-150
  • 34 Ripich D, Vertes D, Whitehouse P, Fulton S, Ekelman B. Turn-taking and speech act patterns in the discourse of senile dementia of the Alzheimer's type patients.  Brain Lang . 1991;  40 330-343
  • 35 Mohs R C, Schmeidler J, Aryan M. Longitudinal studies of cognitive, functional, and behavioral change in patients with Alzheimer's disease.  Stat Med . 2000;  19 1401-1409
  • 36 Schmeidler J, Mohs R C, Aryan M. Relationship of disease severity to decline on specific cognitive and functional measures in Alzheimer disease.  Alzheimer Dis Assoc Disord . 1998;  12 146-151
  • 37 Haley W E, Wadley V G, West A C, Bestzel B A. How caregiving stressors change with severity of dementia.  Semin Speech Lang . 1994;  15 195-205
  • 38 Bayles K A, Tomoeda C K. Caregiver report of prevalence and appearance order of linguistic symptoms in Alzheimer's patients.  Gerontologist . 1991;  31 210-216
  • 39 Hopper T, Bayles K A, Tomoeda C K. Using toys to stimulate communicative function in individuals with AD.  J Med Speech Lang Pathol . 1998;  6 73-80
  • 40 Bourgeois M S. Enhancing conversation skills in patients with Alzheimer's disease using a prosthetic memory aid.  J Appl Behav Anal . 1990;  23 29-42
  • 41 Hopper T, Bayles K A, Harris F P, Holland A. The relation of minimum data set ratings to scores on measures of communication and hearing among nursing home residents with dementia.  Am J Speech Lang Pathol . 2001 (in press); 
  • 42 Holland A L, Boller F, Bourgeois M. Repetition in Alzheimer's disease: a longitudinal study.  J Neurolinguistics . 1986;  2 163-177
  • 43 Santo Pietro J M, Boczko F. The Breakfast Club: results of a study examining the effectiveness of a multi-modality group communication treatment.  Am J Alzheimer's Dis . 1998;  13 146-158
  • 44 Hopper T, Bayles K A. Management of neurogenic communication disorders associated with dementia. In: Chapey R, ed. Language Intervention Strategies in Adult Aphasia and Related Neurogenic Communication Disorders, 4th ed Baltimore: Lippincott Williams & Wilkins 2001: 829-846
  • 45 Brush J A, Camp C J. Using spaced-retrieval as a therapeutic intervention during the rehabilitation process (J Chitwood, director). In: CK Tomoeda (producer), Telerounds Tucson, AZ: The University of Arizona; 1998
  • 46 Francis G, Baly A. Plush animals-do they make a difference?.  Geriatric Nursing . 1986;  74 140-143
  • 47 Milton I, MacPhail J. Dolls and toy animals for hospitalized elders: infantilizing or comforting?.  Geriatric Nursing . 1985;  6 204-206
  • 48 Bayles K A, Tomoeda C K, Cruz R G, Mahendra N. Communication abilities of individuals with late-stage Alzheimer disease.  Alzheimer Dis Assoc Disord . 2000;  14 176-181
  • 49 Beck C. Behavioral treatments for Alzheimer's disease. Paper presented at the Geriatric Research and Education Clinical Center Conference on Alzheimer's Disease, Little Rock, Arkansas; April 25, 2001
  • 50 Reisberg B, Kenowsky S, Franssen E H, Auer S R, Souren L EM. Towards a science of Alzheimer's disease management: a model based upon current knowledge of retrogenesis.  Int Psychogeriatr . 1999;  11 7-23
  • 51 Friedland R P, Krasner B. Managing Alzheimer's patients.  Science . 1998;  282 2194-2195
  • 52 Bayles K A, Tomoeda C K. Functional communication of middle and late stage Alzheimer's patients. Miniseminar presented at the American Speech-Language-Hearing Association Convention, New Orleans, Louisiana; 1994
    >