Planta Med 2001; 67(4): 335-339
DOI: 10.1055/s-2001-14306
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

New Antioxidant and Antimicrobial Ellagic Acid Derivatives from Pteleopsis hylodendron

 Atta-Ur-Rahman1 , F. N. Ngounou2 , M. Iqbal Choudhary1, , Shahid Malik1 , Talat Makhmoor1 , M. Nur-E-Alam1 , Seema Zareen1 , D. Lontsi2 , J. F. Ayafor2 , B. L. Sondengam2
  • 1 International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan
  • 2 Department of Organic Chemistry, Faculty of Science, University of Yaounde 1, Yaounde, Cameroon
Further Information

Publication History

May 26, 2000

July 02, 2000

Publication Date:
31 December 2001 (online)

Abstract

Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3′-O-methyl-4′-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3′-O-methyl ellagic acid (3), 3,3′-di-O-methyl ellagic acid (4) and 3,3′,4′-tri-O-methyl ellagic acid (5), which were obtained for the first time from this plant. The structures of these compounds were elucidated with the help of spectroscopic studies. Compounds 1 and 4 were found to have significant antioxidant activity, while compounds 1 - 4 showed antibacterial activity against different pathogenic bacteria.

References

Prof. M. Iqbal Choudhary

HEJ Research Institute of Chemistry

University of Karachi

Karachi-75270

Pakistan

Email: zainraa@digicom.net.pk

Fax: +92 21 496 3373, 496 3124