Synthesis 2001; 2001(3): 0473-0477
DOI: 10.1055/s-2001-11442
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Conversion of Fused-ring Isoxazolidines to α-(Hydroxymethyl)lactones by 3-Chloroperbenzoic Acid

Massimiliano Arrighi* , Gianluigi Broggini, Alberto Terraneo
  • *Dipartimento di Scienze Chimiche, Fisiche e Matematiche, Università dell'Insubria, via Lucini 3, 22100 Como, Italy; Fax + 39(0 31)32 62 30; E-mail: mabuck@icil64.cilea.it
Further Information

Publication History

Publication Date:
31 December 2001 (online)

MCPBA treatment of fused-ring isoxazolidines furnishes α-(hydroxymethyl)substituted cyclic ketones, which constitute the starting-point for a successive Baeyer-Villiger oxidation allowing the synthesis of novel α-(hydroxymethyl)lactones.

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