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Synthesis 2001; 2001(2): 0339-0342
DOI: 10.1055/s-2001-10799
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Synthesis of an 1′-Azasugar Analogue of Maltose

Vinni Andreassen* , Birte Svensson, Mikael Bols
  • *Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark; Fax +4589411234; E-mail: mb§kemi.aau.dk
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Publication History

Publication Date:
31 December 2001 (online)

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Methyl 1′-azamaltoside (3) was synthesised from levoglucosane and d-galactose in a 16 step synthesis. Methyl 1′-azamaltoside (3) was found to inhibit glucoamylase with K i of 0.63 μM.

glycosidase inhibitor - glucoamylase - reductive amination - isofagomine - glycosides - disaccharides - carbohydrates - nitrogen

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