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Synlett 2001; 2001(2): 0236-0237
DOI: 10.1055/s-2001-10775
DOI: 10.1055/s-2001-10775
letter
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Diels-Alder Cycloaddition of 4,6-Dimethyl-1,2,3-triazine with Enamines, or their Precursors, under Microwave Irradiation
Further Information
Publication History
Publication Date:
31 December 2001 (online)
4,6-Dimethyl-1,2,3-triazine undergoes Diels-Alder cycloaddition with enamines, derived from cyclic ketones, under microwave irradiation within 20 min. This methodology represents a dramatic improvement on the classical method and allows fused pyridine systems to be obtained, in some cases, in good yields.
triazine - microwaves - fused pyridines - Diels-Alder reaction - cyclic ketones