Zusammenfassung.
Zielsetzung: Zur exakten Vermessung aortaler und peripher-arterieller Aneurysmen vor Versorgung
mit Stent-Grafts ist die DSA als projektionsabhängiges Verfahren nur bedingt geeignet.
Untersucht wurde, inwieweit die kontrastmittelverstärkte 3D-MR-Angiographie (3D-KM-MRA)
als Zusatzuntersuchung Nachteile der DSA ausgleichen kann. Patienten und Methoden: 21 Patienten mit 35 Aneurysmen (14 aortal, 9 iliakal, 12 femoropopliteal) erhielten
vor der endoluminalen Behandlung eine DSA mit Messkatheter (7) oder Lineal (14) und
eine 3D-KM-MRA (TR/TE 7,8/2,1 ms, Flip-Winkel 40 °, Matrix 512 × 224, FOV 500 mm,
eff. Schichtd. 1,8 mm). Die Aneurysmen wurden nach Verfahren getrennt befundet und
vermessen. Zur Abschätzung des DSA-Messfehlers wurde die 3D-KM-MRA als projektionsunabhängiges
Referenzverfahren gewertet. Ergebnisse: Innendurchmesser und Länge von Aneurysmen wurden in DSA mit Lineal regelmäßig unterschätzt.
Die Abweichung reichte von 15 % (± 6 %) an der Bauchaorta bis 21 % ( ± 10 %) iliakal.
Längsmaße aus Messkatheter-DSA stimmten mit der MRA überein. In MRA-Einzelschichten
konnten bei 2/35 Aneurysmen Thromben nachgewiesen werden, die die tatsächliche Länge
des Aneurysmas in den DSA maskierten. 2/5 akzessorischen Nierenarterien wurden mit
3D-KM-MRA nicht erkannt. Schlussfolgerungen: Die 3D-KM-MRA ergänzt die DSA bei der Diagnostik aortaler und peripher-arterieller
Aneurysmen. Sie ermöglicht, thrombosierte Anteile zu erfassen und Gefäße frei von
Projektionseffekten zu vermessen.
Gadolinium-enhanced three-dimensional MR angiography before endovascular treatment
of aneurysms in the abdominal aorta, iliac and peripheral vessels.
Purpose: The value of DSA for the measurement of aortic and peripheral arterial aneurysm dimensions
before endovascular treatment is limited by projection effects. It was evaluated if
additional gadolinium-enhanced three-dimensional MR angiography (3D-CEMRA) could compensate
for the disadvantages of DSA. Materials and Methods: 21 patients with 35 aneurysms in the abdominal aorta (14), iliac (9) and femoropopliteal
vessels (12) were assessed with DSA (7 with calibrated catheter, 14 with yardstick)
and 3D-CEMRA (TR/TE 7.8/2.1 ms, flip-angle 40 °, Matrix 512 × 224, FOV 500 mm, eff.
slice 1.8 mm). We measured and compared aneurysm dimensions on both modalities. 3D-CEMRA
was regarded as the reference method to evaluate the dimension of DSA-projection effects.
Results: Diameter and length of aneurysms were underestimated on DSA with the yardstick as
reference. The deviation ranged from 15 % (± 5 %) in the aorta to 21 % (± 10 %) in
the iliac vessels. Only with calibrated catheters as reference (7/21 DSA), were the
distances on DSA correlated well with MRA. In 2/35 aneurysms 3D-CEMRA detected thrombosis
with a difference between length of inner lumen dilatation on DSA and whole aneurysm
length. 2/5 accessory renal arteries found on DSA were not detected on 3D-CEMRA. Conclusions: 3D-CEMRA is a valuable adjunct to DSA for pre-interventional diagnostics of aortic
and peripheral arterial aneurysms. It provides exact evaluation of aneurysm dimensions
and information about partial thrombosis.
Schlüsselwörter:
Aneurysmen - Bauchaorta - Periphere Gefäße - MRA - DSA
Key words:
Aneurysm - Abdominal aorta - Peripheral arteries - MRA - DSA
Literatur
- 1
Blum U, Voshage G, Lammer J, Beyersdorf F, Töllner D, Kretschemer G, Spillner G, Polterauer P,
Nagel G, Hölzenbein T, Thurnher S, Langer M.
Endoluminal stent-grafts for infrarenal abdominal aortic aneurysms.
N Engl J Med.
1997;
336
13-20
- 2
Thurnher S, Dorffner R, Thurnher M, Winkelbauer W, Kretschemer G, Polterauer P, Lammer J.
Evaluation of abdominal aortic aneurysm for stent-graft placement: Comparison of gadolinium-enhanced
MR angiography versus helical CT angiography and digital subtraction angiography.
Radiology.
1997;
205
341-352
- 3
Biederer J, Link J, Steffens J-C, Heller M.
Kontrasmittelverstärkte 3D-MR-Angiographie von Aneurysmen der Becken- und Beinstrombahn.
Gemeinsame Jahrestagung der Norddeutschen Röntgengesellschaft und der Röntgengesellschaft
von Niedersachsen, Bremen und Sachsen-Anhalt am 25. und 26. Februar 2000 in Hamburg.
Fortschr Röntgenstr (Abstract).
2000;
172
307
- 4
Meaney J, Ridgway J, Chakraverty S, Robertson I, Kessel D, Radjenovic A, Kouwenhoven M,
Kassner A, Smith M.
Stepping-table Gadolinium-enhanced digital subtraction MR angiography of the aorta
and lower extremity arteries: Preliminary experience.
Radiology.
1999;
211
59-67
- 5
Vosshenrich R, Castillo E, Kopka L, Rodenwaldt J, Grabbe E.
Kontrastmittelgestützte 3D-MR-Angiographie der peripheren Gefäße in „Schrittverschiebe-Technik”:
Erste Ergebnisse.
Fortschr Röntgenstr.
1998;
168
90-94
- 6
Steffens J, Link J, Brinkmann G, Reuter M, Heller M.
MR-Angiographie der Beckenarterien.
Radiologe.
1997;
37
566-571
- 7
Earls J, DeSena S, Bluemke D.
Gadolinium-enhanced three dimensional MR angiography of the entire aorta and iliac
arteries with dynamic manual table translation.
Radiology.
1998;
209
844-849
- 8
Link J, Steffens J C, Brossmann J, Loose R, Heller M.
Kontrastmittel-MR-Angiographie beim Leriche-Syndrom.
Fortschr Röntgenstr.
1998;
169
22-26
- 9
Holland G, Dougherty L, Carpenter J, Golden M, Gilfeather J, Slossman F, Schnall M,
Axel L.
Breath-hold ultrafast three-dimensional gadolinium-enhanced MR angiography of the
aorta and the renal and other visceral abdominal arteries.
Am J Roentgenol.
1996;
166
971-981
- 10
Prince M.
Gadolinium-enhanced MR aortography.
Radiology.
1994;
191
155-164
- 11
Prince M, Narasimham D, Stanley J, Chenevert T, Williams D, Marx M, Cho K.
Breath-hold gadolinium-enhanced MR angiography of the abdominal aorta and its major
branches.
Radiology.
1995;
197
785-792
- 12
Bosmans H, Marchal G.
Contrast-enhanced MR angiography.
Radiologe.
1996;
36
115-123
- 13
Bogaert J, Meyns B, Rademakers F, Bosmans H, Verschakelen J, Flameng W, Marchal G,
Baert A.
Follow-up of aortic dissection: contribution of MR angiography for evaluation of the
abdominal aorta and its branches.
Eur Radiol.
1997;
7
695-702
- 14
Krinsky G, Rofsky N, DeCorato D, Weinreb J, Earls J, Flyer M, Galloway A, Colvin S.
Thoracic aorta: Comparison of gadolinium-enhanced three-dimensional MR angiography
with conventional MR imaging.
Radiology.
1997;
202
183-193
- 15
Siegelman S, Gilfeather M, Holland A, Carpenter J, Golden M, Townsend R, Schnall M.
Breath-hold ultrafast three-dimensional gadolinium-enhanced MR angiography of the
renovascular system.
Am J Roentgenol.
1997;
168
1035-1040
- 16
Li W, David V, Kaplan R, Edelman R.
Three-dimensional low dose gadolinium-enhanced peripheral MR venography.
J Magn Reson Imaging.
1998;
8
630-633
- 17
Steffens J, Link J, Müller-Hülsbeck S, Freund M, Brinkmann G, Heller M.
Cardiac-gated two-dimensional phase-contrast MR angiography of lower extremity occlusive
disease.
Am J Roentgenol.
1997;
169
749-754
- 18
Busch H, Hoffmann H, Metzner C, Oettinger W.
MR-Angiographie der unteren Extremitäten mit automatischer Tischverschiebung („MobiTrak”)
im Vergleich zur i. a. DSA.
Fortschr Röntgenstr.
1999;
170
275-283
- 19
Link J, Steffens J C, Brossmann J, Graessner J, Hackethal S, Heller M.
Iliofemoral arterial occlusive disease: contrast-enhanced MR angiography for preinterventional
evaluation and follow-up after stent placement.
Radiology.
1999;
212
371-377
- 20
Yamashita Y, Mitsuzaki K, Ogata I, Takahashi M, Hiai Y.
Three-dimensional high-resolution dynamic contrast-enhanced MR angiography of the
pelvis and lower extremities with use of a phased array coil and subtraction: diagnostic
accuracy.
J Magn Reson Imaging.
1998;
8
1066-1072
- 21
Winchester P, Lee H, Khilnani N, Wang Y, Trost D, Bush H, Sos T.
Comparison of two-dimensional MR digital subtraction angiography of the lower extremity
with X-ray angiography.
J Vasc Int Radiol.
1998;
9
891-899
- 22
Wang Y, Lee H, Avakian R, Winchester P, Khilnani N, Trost D.
Timing algorithm for bolus chase MR digital subtraction angiography.
Magn Reson Med.
1998;
39
691-696
- 23
Douek P, Revel D, Chazel S, Falise B, Villard J, Amiel M.
Fast MR angiography of the aortoiliac arteries and arteries of the lower extremity:
Value of bolus-enhanced, whole-volume subtraction technique.
Am J Roentgenol.
1995;
165
431-437
- 24
Rofsky N, Johnson G, Adelman M, Rosen R, Krinsky G, Weinreb J.
Peripheral vascular disease evaluated with reduced-dose gadolinium-enhanced MR angiography.
Radiology.
1997;
205
163-169
- 25
Yamashita Y, Mitsuzaki K, Tang Y, Namimoto T, Takahashi M.
Gadolinium-enhanced breath-hold three-dimensional time-of-flight MR angiography of
the abdominal and pelvic vessels: The value of ultrafast MP-RAGE Sequences.
J Magn Reson Imaging.
1997;
7
623-628
- 26
Prince M, Chenevert T, Foo T, Londy F, Ward J, Maki J.
Contrast-enhanced abdominal MR angiography: Optimization of imaging delay time by
automating the detection of contrast material arrival in the aorta.
Radiology.
1997;
203
109-114
- 27
Earls J, Rofsky N, DeCorato D, Krinky G, Weinreb J.
Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography: Usefulness
of a timing examination and MR power injector.
Radiology.
1996;
201
705-710
- 28
Adamis M, Li W, Wielopolski P, Kim D, Sax E, Kent K, Edelman R.
Dynamic contrast-enhanced subtraction MR angiography of the lower extremities: Initial
evaluation with a multisection two-dimensional time-of-flight sequence.
Radiology.
1995;
196
689-695
- 29
Snidow J, Johnson M, Harris V, Margosian P, Aisen A, Lalka S, Cikrit D, Trerotola S.
Three-dimensional gadolinium-enhanced MR angiography for aortoiliac inflow assessment
plus renal artery screening in a single breath hold.
Radiology.
1996;
198
725-732
- 30
Steffens J, Link J, Grässner J, Müller-Hülsbeck S, Brinkmann G, Reuter M, Heller M.
Contrast-enhanced, K-space-centered, breath-hold MR angiography of the renal arteries
and the abdominal aorta.
J Magn Reson Imaging.
1997;
7
617-622
- 31
Steffens J, Link J, Schwarzenberg H, Müller-Hülsbeck S, Brinkmann G, Heller M.
Lower extremity occlusive disease: Diagnostic imaging with a combination of cardiac-gated
2D phase-contrast and cardiac-gated 2D time-of-flight MRA.
JCAT.
1999;
23
7-12
- 32
Gaa J, Laub G, Edelman R, Georgi M.
Erste klinische Ergebnisse mit der ultraschnellen, kontrastverstärkten 2-Phasen-3D
Angiographie im Abdomen.
Fortschr Röntgenstr.
1998;
169
135-139
Dr. med. Jürgen Biederer
Klinik für Diagnostische Radiologie an der Christian-Albrechts-Universität zu Kiel
Arnold-Heller-Straße 9
24105 Kiel
Telefon: + 49-431-597-3153
Fax: + 49-431-597-3151
eMail: juergen.biederer@rad.uni-kiel.de