Planta Med 2000; 66(6): 585-587
DOI: 10.1055/s-2000-8608
Letter
Georg Thieme Verlag Stuttgart · New York

The Heliangolide Dihydrohirsutolide from Arctotis fastuosa and Dichloromethyldihydrohirsutolide

Ahmed A. Ali1 , Nasr A. El-Emary1 , Azza A. Khalifa1 , Franz-J. Volk2 , August W. Frahm2,*
  • 1 Department of Pharmacognosy, Faculty of Pharmacy, Assiut, Egypt
  • 2 Pharmazeutisches Institut, Universität Freiburg, Freiburg, Germany
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Abstract

Three of ten sesquiterpene lactones isolated from the herb of Arctotis fastuosa (Asteraceae) belong to the heliangolide series. The first was identified as hirsutolide, the second is new and named dihydrohirsutolide, and the third, dichloromethyldihydrohirsutolide, is an artifact. The known degraded carotenoid loliolide was also isolated. Structures were established by spectroscopic methods including IR, 1D-/2D-1H-NMR, 13C-NMR, GHSQC, GHMBC, HREIMS and CD.

References

Prof. Dr. A. W. Frahm

Lehrstuhl für Pharmazeutische Chemie Pharmazeutisches Institut

Hermann-Herder-Strasse 9

79104 Freiburg

Germany

Email: awfrahm@ruf.uni-freiburg.de

Phone: +49 761 203 6351