Abstract
Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate activity was observed for kwakhurin, a prenylated isoflavonoid.
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Prof. Dr. Tsutomu Ishikawa
Faculty of Pharmaceutical Sciences Chiba University
1-33 Yayoi, Inage
Chiba 263-8522
Japan
Email: benti@p.chiba-u.ac.jp
Phone: +81-43-290-2910