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DOI: 10.1055/s-2000-8600
Isolation and Characterization of Cytotoxic Saponin Chloromaloside A from Chlorophytum malayense
Publication History
Publication Date:
31 December 2000 (online)
Abstract
A cytotoxic steroidal glycoside was isolated from Chlorophytum malayense Ridley and its structure was characterized as a known compound, neohecogenin 3-O-β-D-glucopyranosyl(1→2)-[β-D-xylopyranosyl(1→3)]-β-D-glucopyranosyl(1→4)-β-D-galactopyranoside (chloromaloside A). The structural identification was performed using 2D-NMR and LC/MS/MS analysis. The previous, erroneously assigned 1H-NMR spectral data were revised whereas the published 13C-NMR spectral assignments were confirmed. This compound showed in vitro cytotoxicity against several human cancer cell lines.
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Dr. Sheng-Xiang Qiu
Monsanto Company
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