Tamoxifen is of proven efficacy in the treatment of breast cancer. New data indicate
that it might be able to reduce the occurrence of receptor positive breast cancer
when taken as a preventative. However trade-offs for this reduction are an increased
incidence of endometrial carcinomas and thrombo-embolic events. Therefore the use
of tamoxifen as preventative ought to be restricted to clinical studies or a well
defined high risk situation. Whether raloxifen is superior to tamoxifen remains to
be shown.
Tamoxifen - raloxifen - breast cancer - prevention