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Semin Liver Dis 2000; 20(4): 411-424
DOI: 10.1055/s-2000-13153
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Adult-to-Adult Living-Donor Liver Transplantation: A Critical Analysis

John F. Renz1,2 , Ronald W. Busuttil2
  • 1Department of Surgery, University of California San Francisco, California
  • 2The Dumont-UCLA Liver Transplantation Center, University of California, Los Angeles, Los Angeles, California
Further Information

Publication History

Publication Date:
31 December 2000 (online)

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ABSTRACT

Adult-to-adult living-donor liver transplantation is the most recent achievement in the evolution of strategies to increase donor organ supply. Justification of the procedure has evolved from increased organ-waiting times, wait-list morbidity and mortality of adult transplant candidates. Successful application of adult-to-adult living-donor liver transplantation mandates unique surgical, medical, and donor considerations as these procedures predispose to unique complications resulting from anatomic variations, technical considerations, and the transplantation of ``partial'' grafts. Additionally, because the magnitude of the donor operation is greater and potentially fraught with serious short and long term morbidity and possibly mortality, the utilization of living-donors for adult liver transplantation raises bio-ethical concerns heretofore not encountered. This review explores the current state of adult-to-adult living-donor liver transplantation.

KEYWORD

adult living-donor liver transplantation - organ donation - liver - liver transplant surgery

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