Steroids from Harrisonia abyssinica

Aliou M. Baldé; Sandra Apers; Tess E. De Bruyne; Hilde Van Den Heuvel; Magda Claeys; Arnold J. Vlietinck; Luc A. C. Pieters

doi:10.1055/s-2000-11120

Planta Medica, Table of Contents

Planta Med 2000; 66(1): 67-69
DOI: 10.1055/s-2000-11120

Original Paper

Georg Thieme Verlag Stuttgart · New York

Steroids from Harrisonia abyssinica

Aliou M. Baldé¹ , Sandra Apers² , Tess E. De Bruyne² , Hilde Van Den Heuvel² , Magda Claeys² , Arnold J. Vlietinck², and, Luc A. C. Pieters^2,*

¹ Faculté de Médecine-Pharmacie-Odontologie, Université de Conakry, Guinée (present address)
² Department of Pharmaceutical Sciences, University of Antwerp (UIA), Antwerp, Belgium

Abstract

In addition to the known sterols and ketosteroids β-sitosterol (24α-ethylcholest-5-en-3β-ol), stigmasterol (24α-ethylcholesta-5,22-dien-3β-ol), campesterol (24α-methylcholest-5-en-3β-ol), β-sitostenone (stigmast-4-en-3-one, 24α-ethylcholest-4-en-3-one), stigmastenone (stigmasta-4,22-dien-3-one, 24α-ethylcholesta-4,22-dien-3-one), campestenone (24α-methylcholest-4-en-3-one), and stigmasta-3,5-dien-7-one (24α-ethylcholesta-3,5-dien-7-one), the new steroids stigmasta-3,5,22-trien-7-one (24α-ethylcholesta-3,5,22-trien-7-one), and campesta-3,5-dien-7-one (24α-methylcholesta-3,5-dien-7-one) were isolated from the stem bark of Harrisonia abyssinica and identified by NMR and mass spectrometry.

Key words

Harrisonia abyssinica - Simaroubaceae - ketosteroids

Full Text

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Prof. Dr. L. Pieters

Department of Pharmaceutical Sciences

University of Antwerp

Universiteitsplein 1

B-2610 Antwerp

Belgium

Email: pieters@uia.ua.ac.be

Phone: +32 3 820 27 09