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Synlett 1996; 1996(7): 623-624
DOI: 10.1055/s-1996-5542
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Synthesis of Dihydropyrrolo[2,1-a]isoquinolines by Regioselective [3+2] Cyclocondensation

Péter Nemes, Mária Kajtár-Peredy, Pál Scheiber*
  • *Department of Chemistry, University of Veterinary Science, H-1400 Budapest, P.O.Box 2, Hungary
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Publication Date:
31 December 2000 (online)

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The synthesis of 2,3-dialkyl-5,6-dihydropyrrolo[2,1-a]isoquinolines from 1-chloromethyl-3,4-dihydroisoquinoline and aliphatic ketones is described. The cyclocondensations took place with high regioselectivity in all cases.

[3+2] cyclocondensation - 1,3-dipole of imino-carbene type - dihydropyrrolo[2,1-a]isoquinolines

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