Download PDF
Synlett 1994; 1994(12): 1031-1033
DOI: 10.1055/s-1994-23075
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Enantioselective Intramolecular C-H Insertion Reactions of N-Alkyl-N-tert-Butyl-α-Methoxycarbonyl-α-Diazoacetamides Catalyzed by Dirhodium(II) Carboxylates: Catalytic, Asymmetric Construction of 2-Azetidinones

Nobuhide Watanabe* , Masahiro Anada, Shun-ichi Hashimoto, Shiro Ikegami
  • *Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060, Japan
Further Information

Publication History

Publication Date:
22 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Intramolecular C-H insertion reaction of N-alkyl-N-tert-butyl-α-methoxycarbonyl-α-diazoacetamides has been catalyzed by dirhodium(II) tetrakis[N-phthaloyl-(S)-phenylalaninate] to afford 4-substituted 1-tert-butyl-3-methoxycarbonyl-2-azetidinones with 3,4-cis stereochemistry in up to 74% ee.

      >