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Synlett 1992; 1992(4): 266-268
DOI: 10.1055/s-1992-21334
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A Short and Efficient Synthesis of a C1-C9 Intermediate Towards Maytansine

Michel Bénéchie* , Françoise Khuong-Huu
  • *CNRS-Institut de Chimie des Substances Naturelles, F-91198 Gif-sur-Yvette, France
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Publication Date:
08 March 2002 (online)

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A short synthesis of highly functionalised 3S,6R,7S)-4-nonene 1, C1-C9 intermediate for maytansine, was achieved starting from propyne and (S,S)-1-(p-toluenesulphonyloxy) -2,3-epoxybutane (3).

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