Download PDF
Synlett 1991; 1991(5): 310-312
DOI: 10.1055/s-1991-34721
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Enzymatic Synthesis of Enantiomerically Pure Chiral Synthons: Lipase-Catalyzed Resolution of (R/S, 4E)-2-Methyl-4-hexen-l-ol

Patrizia Ferraboschi* , Daria Brembilla, Paride Grisenti, Enzo Santaniello
  • *Dipartimento di Chimica e Propedeutica Biochimica, Università degli Studi di Milano, Via Saldini 50, I-20133 Milano, Italy
Further Information

Publication History

Publication Date:
07 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The synthetically useful chiral synthons R and S (4E)-2-methyl-4-hexen-1-ol (1a) can be prepared enantiomerically pure by an enantioselective transacetylation with vinyl acetate of racemic 1a in dichloromethane catalyzed by a lipase from Pseudomonas fluorescens (PFL).

      >