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Synthesis 1989; 1989(11): 861-862
DOI: 10.1055/s-1989-27412
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A Convenient Synthesis of Ethyl (Diethoxyphosphoryl) fluoroacetate from Ethyl Fluoroacetate

Elias Elkik* , Michèle Imbeaux
  • *Ecole Normale Supérieure, Département de Chimie, UA1110 du CNRS, Laboratoire de l'Activation Moléculaire, Laboratoire de l'Université Pierre et Marie Curie, 24 rue Lhomond, F-75231 Paris Cedex 05, France
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Publication Date:
02 May 2002 (online)

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A new synthesis of ethyl (diethoxyphosphoryl)fluoroacetate starting from ethyl fluoroacetate is described for a mole scale. This synthesis does not require the use of special equipment for fluorine chemistry since no hydrogen fluoride is evolved.

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