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Synthesis 1989; 1989(4): 314-316
DOI: 10.1055/s-1989-27239
DOI: 10.1055/s-1989-27239
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Synthesis of Some Nitropyridylacetonitriles
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Publication History
Publication Date:
17 September 2002 (online)
A new synthesis of nitropyridylacetonitriles 4 has been developed, using tert-butyl cyanoacetate and the corresponding chloropyridines 2. The tert-butyl esters are removed by acid-catalyzed dealkoxycarbonylation.