Oxidative Cleavage of 7-Oxo-6,7-dihydroisoxazolo[3,4-d] pyridazines by Cerium(IV) Diammonium Nitrate. A Synthetic Approach to New 5-Acyl-4-nitro-3-oxo-2,3-dihydropyridazines

Vittorio Dal Piaz; Giovanna Ciciani; Giovanni Turco

doi:10.1055/s-1989-27204

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Synthesis 1989; 1989(3): 213-214
DOI: 10.1055/s-1989-27204

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Oxidative Cleavage of 7-Oxo-6,7-dihydroisoxazolo[3,4-d] pyridazines by Cerium(IV) Diammonium Nitrate. A Synthetic Approach to New 5-Acyl-4-nitro-3-oxo-2,3-dihydropyridazines

Vittorio Dal Piaz^* , Giovanna Ciciani, Giovanni Turco

^*Dipartimento di Scienze Farmaceutiche, Università di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy

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Publication Date:
17 September 2002 (online)

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5-Acyl-4-nitro-3-oxo-2,3-dihydropyridazines 3 were prepared by heating 7-oxo-6,7-dihydroisoxazolo[3,4-d]pyridazines, 2 with cerium(IV) diammonium nitrate in dilute acetic and nitric acid.

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