Synthesis 1988; 1988(12): 1003-1004
DOI: 10.1055/s-1988-27787
communication
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Drastische Ausbeutesteigerungen bei Cyclisierungen zu gespannten Heterocyclen mittlerer Ringgröße

Andreas Ostrowicki* , Fritz Vögtle
  • *Institut für Organische Chemie und Biochemie der Universität, Gerhard-Domagk Straße 1, D-5300 Bonn 1, Federal Republic of Germany
Further Information

Publication History

Publication Date:
20 August 2002 (online)

Dramatic Yield Increase in Cyclizations Leading to Strained Heterocycles of Medium Ring Size By careful choice of the cyclization conditions (solvent, concentration of cesium hydroxide, high dilution) several strained heterocyclic metacyclophanes could be obtained in dramatically increased yields. The favorable effect of cesium hydroxide on the yield was proven.

    >