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Synthesis 1988; 1988(11): 888-890
DOI: 10.1055/s-1988-27739
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Metalation Reactions; Part XI. A Novel, One-Step Synthesis of Benzo[b]thiophene Derivatives

S. Cabiddu* , D. Cancellu, C. Floris, G. Gelli, S. Melis
  • *Istituto di Chimica Organica dell'Università, Via Ospedale n. 72, I-09124 Cagliari, Italy
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Publication Date:
20 August 2002 (online)

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A novel one-step synthesis of 3-substituted benzo[b]thiophene derivatives was achieved by dilithiation of (methylthio)benzene followed by reaction with varous aliphatic and aromatic carboxylic acid chlorides.

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