Synthesis 1988; 1988(4): 323-325
DOI: 10.1055/s-1988-27557
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Abnormal Ring Opening of 1,2-Epoxyalkyldiphenylphosphine Oxides with Lithium Aluminum Hydride to Form 2-Hydroxy-alkyldiphenylphosphine Oxides

Hiroyuki Imoto* , Mitsuji Yamashita
  • *Department of Applied Chemistry, Faculty of Engineering, Shizuoka University, Hamamatsu 432, Japan
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Publikationsdatum:
20. August 2002 (online)

Ring opening of 1,2-epoxyalkyldiphenylphosphine oxides with LiAlH4 gives 2-hydroxyalkyldiphenylphosphine oxides in good yield. This is the first example of ring opening of 1,2-epoxyalkyldiphenylphosphine oxides to give the corresponding 2-hydroxy derivatives.

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