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Synthesis 1988; 1988(4): 307-310
DOI: 10.1055/s-1988-27550
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A Facile Conversion of Aminoalkanephosphonic Acids into Their Diethyl Esters. The Use of Unblocked Aminoalkanephosphonic Acids in Phosphono Peptide Synthesis

Paweł Kafarski* , Barbara Lejczak
  • *Institute of Organic and Physical Chemistry, Technical University of Wrocław, Wybrzeże Wyspiańskiego 27, PL-50370 Wrocław, Poland
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Publication Date:
20 August 2002 (online)

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A simple and efficient, two-step procedure for the preparation of diethyl aminoalkylphosphonates from aminoalkylphosphonic acids is reported. The obtained esters are useful as substrates in phosphono peptide synthesis.

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