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Synthesis 1986; 1986(1): 70-71
DOI: 10.1055/s-1986-31482
DOI: 10.1055/s-1986-31482
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A Palladium-Catalyzed Synthesis of 4-Aryl-2-oxo-2,5-dihydrofurans [4-Aryl-2(5H)-furanones]
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Publication Date:
20 August 2002 (online)
Palladium-catalyzed arylation of methyl (E)-4-(2-tetrahydropyranyloxy)-2-butenoate with aryl iodides and intramolecular cyclocondensation of the resultant 3-aryl derivatives affords 4-aryl-2-oxo-2,5-dihydrofurans in moderate to good yields.