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DOI: 10.1055/s-0045-1812066
CLOVES Syndrome: An Unusual Cause of Vascular Malformations and Soft Tissue Overgrowth
Authors
Funding None.
Abstract
CLOVES syndrome is a rare congenital disorder characterized by Congenital Lipomatous Overgrowth of the trunk and/or thorax, Vascular malformations, skin abnormalities (such as linear Epidermal nevi), and Skeletal anomalies, with scoliosis and tethered cord being common features. This report presents the case of a 17-year-old boy with clinical and imaging features consistent with CLOVES syndrome, confirmed by genetic analysis demonstrating a somatic PIK3CA mutation.
Publication History
Article published online:
07 October 2025
© 2025. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
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