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CC BY 4.0 · Brazilian Journal of Oncology 2026; 22: s00451811730
DOI: 10.1055/s-0045-1811730
Original Article
Surgical Oncology

Epidemiology of Spinal Metastases and Postsurgical Outcomes

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Abstract

Spinal metastases are a common complication of systemic malignancies, significantly affecting patients' quality of life and survival. This observational and retrospective study aims to evaluate the epidemiological characteristics of patients undergoing surgery for spinal metastases at A.C. Camargo Cancer Center, as well as their functional status up to 60 days postsurgery. Medical records of patients treated between March 2022 and August 2024 were analyzed, including variables such as age, sex, tumor type, pre- and postsurgical functional status, metastasis location, and the type of intervention performed. The outcomes analyzed include postsurgical functional status, hospital discharge rates, hospitalization periods, and mortality rates. The analysis was conducted using the Stata 13 (StataCorp LLC.) software with appropriate statistical tests. The results provide an updated overview of the clinical profile and functional outcomes of operated patients, helping optimize the management of spinal metastases.

Keywords

metastasis - spine - neurosurgery

Authors' Contributions

All authors have contributed on conceptualization, data curation, formal analysis, funding acquisition, investigation, methodology, project administration, resources, software, supervision, validation, visualization, writing – original draft, writing – review & editing.


The present work was conducted at the AC Camargo Cancer Center, São Paulo, SP, Brazil.




Publication History

Received: 04 April 2025

Accepted: 15 July 2025

Article published online:
04 February 2026

© 2026. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Anibal Rodrigues Neto, Eloah Silva Marcilio, Shiro Manoel Shimoakoishi de Arruda, Raphael Esteves Veiga, Robson Tadashi Saruwatari, Sergio Hideki Suzuki, Vinicius Trindade Gomes da Silva, Jose Erasmo Dal'Col Lucio. Epidemiology of Spinal Metastases and Postsurgical Outcomes. Brazilian Journal of Oncology 2026; 22: s00451811730.
DOI: 10.1055/s-0045-1811730
 

  • References

  • 1 Sciubba DM, Gokaslan ZL. Diagnosis and management of metastatic spine disease. Surg Oncol 2006; 15 (03) 141-151
    Search in Google Scholar
  • 2 Patchell RA, Tibbs PA, Regine WF, Payne R, Saris S, Kryscio RJ. et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 2005; 366 (9486) 643-648
    Search in Google Scholar
  • 3 Bilsky MH, Boakye M, Collignon F, Kraus D, Boland P. Operative management of metastatic and malignant primary subaxial cervical tumors. J Neurosurg Spine 2005; 2 (03) 256-264
    Search in Google Scholar
  • 4 Fourney DR. et al. En bloc resection of primary and metastatic tumors of the cervical spine: classification, technique, and outcomes. Spine 2003; 28 (18) E375-E387
    Search in Google Scholar
  • 5 Rades D, Abrahm JL. The role of radiotherapy for metastatic epidural spinal cord compression. Nat Rev Clin Oncol 2010; 7 (10) 590-598
    Search in Google Scholar
  • 6 Rades D, Dunst J, Schild SE. The first score predicting overall survival in patients with metastatic spinal cord compression. Cancer 2008; 112 (01) 157-161
    Search in Google Scholar
  • 7 Laufer I, Rubin DG, Lis E, Cox BW, Stubblefield MD, Yamada Y, Bilsky MH. The NOMS framework: approach to the treatment of spinal metastatic tumors. Oncologist 2013; 18 (06) 744-751
    Search in Google Scholar
  • 8 Cole JS, Patchell RA. Metastatic epidural spinal cord compression. Lancet Neurol 2008; 7 (05) 459-466
    Search in Google Scholar
  • 9 Araujo JLV, Veiga JCE, Figueiredo EG, Barboza VR, Daniel JW, Panagopoulos AT. Management of metastatic spinal column neoplasms - an update [Manejo das neoplasias metastáticas da coluna vertebral - uma atualização]. Rev Col Bras Cir 2013; 40 (06) 508-513
    Search in Google Scholar
  • 10 Van den Brande R, Cornips EMJ, Peeters M, Ost P, Billiet C, Van de Kelft E. Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review. J Bone Oncol 2022; 35: 100446
    Search in Google Scholar
  • 11 Jaipanya P, Lertudomphonwanit T, Chanplakorn P, Pichyangkul P, Kraiwattanapong C, Keorochana G, Leelapattana P. Predictive factors for respiratory failure and in-hospital mortality after surgery for spinal metastasis. Eur Spine J 2023; 32 (05) 1729-1740
    Search in Google Scholar
  • 12 Kirshblum S, Snider B, Rupp R, Read MS. International Standards Committee of ASIA and ISCoS. Updates of the International Standards for Neurologic Classification of Spinal Cord Injury: 2015 and 2019. Phys Med Rehabil Clin N Am 2020; 31 (03) 319-330
    Search in Google Scholar
  • 13 Rodrigues LM, Valesin Filho ES, Ueno FH, Fujiki EN, Milani C. Quality of life of patients submitted to decompression for metastatic vertebral lesion [Qualidade de vida de pacientes submetidos à descompressão por lesão vertebral metastática]. Acta Ortop Bras 2011; 19 (03) 149-153
    Search in Google Scholar