Subscribe to RSS

DOI: 10.1055/s-0045-1811704
Perioperative Complications During Posterior Fossa Surgery in Sitting Position: A Single-Center Retrospective Study
Authors

Abstract
Background
Sitting position used to be a favored position for posterior fossa surgery. Its use has declined owing to the increased incidence of life-threatening complications. Our center continues to practice sitting craniotomy, although less frequently. This study aimed to determine the incidence of perioperative complications during sitting craniotomy.
Methods
Medical records of 206 patients who underwent posterior fossa surgery in sitting position over a 10-year period were analyzed. Data on demographics, perioperative complications, and neurological status were recorded. Statistical analysis was done using the chi-square and the Wilcoxon rank-sum tests, and a p-value of < 0.05 was considered significant.
Results
Out of 206 eligible patients, 188 had near-complete data. A declining trend was observed in the use of the sitting position. Thirty-nine patients presented with episodes of venous air embolism (VAE) with an incidence of 20.7%. No correlation was found between cerebrospinal fluid draining procedures or previous craniotomy and the development of VAE. None of the patients reported other perioperative complications except one who developed tension pneumocephalus. Intraoperative brainstem handling was the most common reason (72%) for postoperative mechanical ventilation. At discharge, 166 (88.3%) patients had good neurological outcomes, while poor outcomes were seen in 4 and mortality in 15 (7.9%), respectively.
Conclusion
The incidence of perioperative complications with the sitting position was not unusually high to prevent its routine use. Moreover, the development of VAE was not associated with increased complications or patient mortality risk. The use of sitting craniotomy, while debatable, continues to be safe in expert hands.
Publication History
Article published online:
18 September 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Black S, Ockert DB, Oliver WC, Cucchiara RF. Outcome following posterior fossa craniectomy in patients in the sitting or horizontal positions. Anesthesiology 1988; 69 (01) 49-56
- 2 Young ML, Smith DS, Murtagh F, Vasquez A, Levitt J. Comparison of surgical and anesthetic complications in neurosurgical patients experiencing venous air embolism in the sitting position. Neurosurgery 1986; 18 (02) 157-161
- 3 Rath GP, Bithal PK, Chaturvedi A, Dash HH. Complications related to positioning in posterior fossa craniectomy. J Clin Neurosci 2007; 14 (06) 520-525
- 4 Gupta P, Rath G, Prabhakar H, Bithal P. Complications related to sitting position during pediatric neurosurgery: an institutional experience and review of literature. Neurol India 2018; 66 (01) 217
- 5 McAllister RG. Macroglossia–a positional complication. Anesthesiology 1974; 40 (02) 199-200
- 6 Matjasko J, Petrozza P, Cohen M, Steinberg P. Anesthesia and surgery in the seated position: analysis of 554 cases. Neurosurgery 1985; 17 (05) 695-702
- 7 Toung T, Donham RT, Lehner A, Alano J, Campbell J. Tension pneumocephalus after posterior fossa craniotomy: report of four additional cases and review of postoperative pneumocephalus. Neurosurgery 1983; 12 (02) 164-168
- 8 Elton RJ, Howell RSC. The sitting position in neurosurgical anaesthesia: a survey of British practice in 1991 †. Br J Anaesth 1994; 73 (02) 247-248
- 9 Orliaguet GA, Hanafi M, Meyer PG. et al. Is the sitting or the prone position best for surgery for posterior fossa tumours in children?. Paediatr Anaesth 2001; 11 (05) 541-547
- 10 Ganslandt O, Merkel A, Schmitt H. et al. The sitting position in neurosurgery: indications, complications and results. a single institution experience of 600 cases. Acta Neurochir (Wien) 2013; 155 (10) 1887-1893
- 11 Lumb AB, Nunn JF. Respiratory function and ribcage contribution to ventilation in body positions commonly used during anesthesia. Anesth Analg 1991; 73 (04) 422-426
- 12 Slotty PJ, Abdulazim A, Kodama K. et al. Intraoperative neurophysiological monitoring during resection of infratentorial lesions: the surgeon's view. J Neurosurg 2017; 126 (01) 281-288
- 13 Wilson JTL, Pettigrew LEL, Teasdale GM. Structured interviews for the Glasgow Outcome Scale and the Extended Glasgow Outcome Scale: guidelines for their use. J Neurotrauma 1998; 15 (08) 573-585
- 14 McMillan TM, Weir CJ, Ireland A, Stewart E. The Glasgow Outcome at Discharge Scale: an inpatient assessment of disability after brain injury. J Neurotrauma 2013; 30 (11) 970-974
- 15 Cucchiara RF, Nugent M, Seward JB, Messick JM. Air embolism in upright neurosurgical patients: detection and localization by two-dimensional transesophageal echocardiography. Anesthesiology 1984; 60 (04) 353-355
- 16 Papadopoulos G, Kuhly P, Brock M, Rudolph KH, Link J, Eyrich K. Venous and paradoxical air embolism in the sitting position. A prospective study with transoesophageal echocardiography. Acta Neurochir (Wien) 1994; 126 (2–4): 140-143
- 17 Harrison EA, Mackersie A, McEwan A, Facer E. The sitting position for neurosurgery in children: a review of 16 years' experience. Br J Anaesth 2002; 88 (01) 12-17
- 18 Bithal PK, Pandia MP, Dash HH, Chouhan RS, Mohanty B, Padhy N. Comparative incidence of venous air embolism and associated hypotension in adults and children operated for neurosurgery in the sitting position. Eur J Anaesthesiol 2004; 21 (07) 517-522
- 19 Baro V, Lavezzo R, Marton E. et al. Prone versus sitting position in pediatric low-grade posterior fossa tumors. Childs Nerv Syst 2019; 35 (03) 421-428
- 20 Losasso TJ, Muzzi DA, Dietz NM, Cucchiara RF. Fifty percent nitrous oxide does not increase the risk of venous air embolism in neurosurgical patients operated upon in the sitting position. Anesthesiology 1992; 77 (01) 21-30