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DOI: 10.1055/s-0045-1811654
Exploring the Medication Patterns of Professor Zulong Wang in Treating Sleep-Related Painful Erection Based on Data Mining
Authors
Funding This study was supported by the National Natural Science Foundation of China General Program (82174377) and National Traditional Chinese Medicine Advantageous Specialty Construction Project (GZY-ZY [2024]90).
Abstract
Objective
To explore the medication patterns of Professor Zulong Wang in treating sleep-related painful erection (SRPE) through data mining, aiming to discover new therapeutic strategies for traditional Chinese medicine in managing this condition.
Methods
Medical records of SRPE patients treated by Professor Zulong Wang at the First Affiliated Hospital of Henan University of Chinese Medicine from February 2021 to December 2024 were collected to establish a database. Frequency analysis, association rule analysis, and cluster analysis were employed to examine the frequency of herb use, four properties and five flavors, channel tropisms, and herb combinations.
Results
A total of 59 prescriptions meeting the criteria were included, involving 81 Chinese herbs, among which 27 herbs were used 10 or more times. The primary herb properties were cold, warm, and neutral, with bitter, sweet, and pungent flavors being most common. The herbs predominantly entered the liver, heart, spleen, and kidney channels. Forty-three commonly used herb combinations were identified, and cluster analysis revealed six core herb groups.
Conclusion
Professor Zulong Wang primarily treats SRPE with modified Huoluo Xiaoling Dan, focusing on unblocking collaterals and relieving pain, supplemented by soothing the liver and regulating qi, resolving stasis and phlegm, nourishing yin and reducing fire, and tonifying the kidney and activating blood circulation.
Keywords
sleep-related painful erection - medication patterns - Huoluo Xiaoling Dan - unblocking collaterals and relieving pain - Zulong Wang - traditional Chinese medicineCRediT Authorship Contribution Statement
Hanbin Zhao: Conceptualization, data curation, formal analysis, investigation, and writing-original draft. Miaomiao Ma: Project administration, supervision, and writing-review and editing. Yuanyuan Li: Data curation, formal analysis, and ethodology. Guangzhao Wang: Data curation, formal analysis, and investigation. Wenbo Zhu: Data curation, formal analysis, and investigation. Zulong Wang: Supervision and writing-review & editing.
Publikationsverlauf
Eingereicht: 10. April 2025
Angenommen: 07. Juli 2025
Artikel online veröffentlicht:
30. September 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Georg Thieme Verlag KG
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