Subscribe to RSS

DOI: 10.1055/s-0045-1811598
Asymmetrical Brachial Plexus Involvement with Greater Auricular Nerve Involvement in Borderline Tuberculoid Leprosy: An Electrophysiological and Radiological Correlation
Authors
Funding None.

Abstract
Leprosy, caused by Mycobacterium leprae, is known for mainly affecting the peripheral nerves. But in recent years, there is growing recognition that it can also involve the central nervous system, including the spinal cord and the brachial plexus. This broader understanding of nerve involvement highlights the importance of newer diagnostic tools like nerve conduction studies, high-resolution ultrasonography, and magnetic resonance imaging, which can help detect and assess these deeper structures and more complex manifestations. We present an intriguing case of a 27-year-old male diagnosed with borderline tuberculoid leprosy based on histopathology, who was found to have brachial plexopathy on nerve conduction studies and magnetic resonance imaging, along with involvement of the greater auricular nerve as revealed by high-resolution ultrasonography.
Keywords
asymmetrical brachial plexopathy - greater auricular nerve - high-resolution ultrasound - magnetic resonance imaging - nerve conduction studyPublication History
Article published online:
16 September 2025
© 2025. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Bhoi SK, Naik S, Purkait S. Pure neuritic leprosy with bilateral foot drop and central nervous involvement: a clinical, electrophysiological, and MR correlation. Neurol India 2021; 69 (05) 1349-1353
- 2 Mittal A, Dhanota DPS, Saggar K, Ahluwalia A. Brachial plexopathy with ulnar nerve abscess in leprosy: a case showing importance of magnetic resonance neurography with clinical, imaging and histopathological correlation. Indian J Dermatol Venereol Leprol 2022; 88 (03) 385-388
- 3 Nalini A, Singh RJ, Saini J, Prasad C, Mahadevan A. Magnetic resonance neurography identifies involvement of plexuses in leprous neuropathy. Neurol India 2015; 63 (04) 624-626
- 4 Nisargandha MA, Parwe SD, Lade NR, Padathpeedika Khalid J, Kuchewar VV. Assessing nerve conduction velocity as a diagnostic and prognostic indicator in leprosy patients: a cross-sectional study. Cureus 2024; 16 (04) e58294
- 5 Jabeen S, Saini J, Vengalil S. et al. Neuroimaging in leprosy: the nerves and beyond. Radiol Infect Dis 2020; 7 (01) 12-21
- 6 Polavarapu K, Preethish-Kumar V, Vengalil S. et al. Brain and spinal cord lesions in leprosy: a magnetic resonance imaging–based study. Am J Trop Med Hyg 2019; 100 (04) 921-931
- 7 Elangovan K, Kumar S, Garg RK. et al. Neuroimaging in leprosy: a case series exploring domains beyond peripheral nerves. Cureus 2025; 17 (04) e81571
- 8 Verma S, Garg RK, Rizvi I. et al. Central nervous system, spinal root ganglion and brachial plexus involvement in leprosy: a prospective study. J Cent Nerv Syst Dis 2022; 14: 11 795735221135477
- 9 DeFaria CR, Silva IM. Electromyographic diagnosis of leprosy. Arq Neuropsiquiatr 1990; 48 (04) 403-413
- 10 Poojar M, Singh R, Nalini A. et al. Neurography in Hansen's neuritis (P6. 030). Neurology 2015; 84 (14, Suppl): 6-030
- 11 Ghia D, Gadkari R, Nayak C. Complex regional pain syndrome secondary to leprosy. Pain Med 2012; 13 (08) 1067-1071