Abstract
Introduction
Hemorrhoids are common anorectal conditions characterized by swollen and inflamed
veins in the rectal and anal regions. They are classified as internal, external, or
mixed, and may present with rectal bleeding, pain, itching, and prolapse. Chronic
constipation, prolonged straining, and increased intra-abdominal pressure are frequent
etiological factors. Management strategies range from conservative measures, such
as dietary modifications and topical agents, to surgical procedures including hemorrhoidectomy
and stapled hemorrhoidopexy.
Objective
To describe the therapeutic potential of hyaluronic acid (HA) in the management of
hemorrhoids and to report clinical outcomes in patients treated with HA infiltration.
Results
Five patients with hemorrhoids underwent HA infiltration. Treatment was associated
with significant symptom relief, reduced edema, and improved post-surgical recovery.
The mechanism of action involved enhanced fibroblast activity, decreased inflammatory
cytokines, and improved mucosal hydration.
Conclusion
Hyaluronic acid demonstrates promising results as a safe and effective option for
hemorrhoid management. Its hydrating, anti-inflammatory, and wound-healing properties
support its role as a versatile therapeutic agent in both conservative and surgical
settings, contributing to improved patient outcomes.
Keywords
hemorrhoids - hemorrhoidectomy - hyaluronic acid - proctology
Bibliographical Record
Riddhi Upadhyay, Akshat Vadaliya, Haryax V. Pathak, Soham Upadhyay. Enhancing Proctological
Outcomes: The Role of Hyaluronic Acid in Hemorrhoid Care – An Innovative Adjunct to
Surgery. Journal of Coloproctology 2025; 45: s00451811263.
DOI: 10.1055/s-0045-1811263
