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CC BY-NC-ND 4.0 · Asian J Neurosurg 2025; 20(04): 780-784
DOI: 10.1055/s-0045-1811243
Original Article

Clinical Features and Post-Coiling Outcomes of Symptomatic Internal Carotid Artery–Posterior Communicating Artery Aneurysms: A Case Series and Literature Review

Authors

  • Daisuke Wajima

    1   Department of Neurosurgery, Kanazawa University, Ishikawa-ken, Kanazawa, Japan

  • Tomoya Kamide

    1   Department of Neurosurgery, Kanazawa University, Ishikawa-ken, Kanazawa, Japan

  • Mitsutoshi Nakada

    1   Department of Neurosurgery, Kanazawa University, Ishikawa-ken, Kanazawa, Japan
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Abstract

Objective

This article aims to understand the clinical course of symptomatic internal carotid artery (ICA)–posterior communicating artery (PCom) aneurysms and the outcomes of post-coiling for unruptured symptomatic aneurysms by analyzing the anatomical imaging data and patient backgrounds of patients treated in our institute in the last 5 years.

Materials and Methods

This study enrolled 82 patients with ICA-PCom aneurysms. Anatomical factors, including age, sex, side, aneurysm dome and neck size, aneurysm depth/neck width ratio (ASPECT ratio), family history of cerebral aneurysm, history of hypertension, smoking habit, angle between aneurysm dome protrusion and ICA C2 portion, angle between ICA C2 and C3 portions, and PCom diameter, were analyzed. In the outcome analysis of coil embolization for symptomatic unruptured ICA-PCom aneurysms, we evaluated age, sex, side, aneurysm dome and neck side, ASPECT ratio, volume embolization ratio, and time from onset.

Statistical Analysis

Mann–Whitney U and Fisher's exact tests were utilized for quantitative and categorical variables, respectively.

Results

In both ruptured and unruptured ICA-PCom aneurysms, the angle between the aneurysm dome protrusion and ICA C2 portion and the angle between the ICA C2 and C3 portions were smaller in the oculomotor palsy group than in the nonoculomotor palsy group. Other factors such as age, sex, side, aneurysm dome, neck, ASPECT ratio, family history, hypertension, smoking, and PCom diameter did not significantly influence oculomotor palsy. Early coil embolization led to better recovery of neural function, with immediate intervention offering the highest chance of full recovery.

Conclusion

Overall, this study showed that sharp ICA siphon and aneurysm dome protrusion are significant factors in symptomatic ICA-PCom aneurysms. We propose that immediate surgery be recommended for patients with ICA-PCom aneurysm-induced oculomotor nerve palsy to prevent functional disability and potential aneurysm rupture.

Keywords

internal carotid artery–posterior communicating artery aneurysm - internal carotid artery siphon - aneurysm dome protrusion - oculomotor nerve palsy - angle

Ethical Approval

This study was approved by our institutional review board.




Publication History

Article published online:
21 August 2025

© 2025. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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